Opportunity Information: Apply for PAR 16 357
The Avenir Award Program for Genetics or Epigenetics of Substance Use Disorders (DP1) is a National Institutes of Health (NIH) funding opportunity from the National Institute on Drug Abuse (NIDA) designed to push the field forward by backing bold, high-impact ideas at an early stage. "Avenir" means "future" in French, and the program is intentionally aimed at early stage investigators who have strong, innovative research concepts but may not yet have the extensive preliminary data typically expected for a standard R01 grant. The overall goal is to identify and support researchers who show clear potential to become future leaders, especially those proposing creative approaches that could meaningfully advance understanding of the genetics or epigenetics underlying substance use disorders.
The scientific focus of this specific Avenir program is on genetics and epigenetics related to substance use disorders, distinguishing it from NIDA's other Avenir track that focuses on HIV/AIDS research. While the full scientific scope is not laid out in the excerpt, the title and framing make it clear the program is meant to catalyze innovative work that connects genetic factors (such as inherited variation) and epigenetic mechanisms (such as environmentally influenced changes in gene regulation) to the development, progression, risk, or biology of substance use disorders. In practice, this type of funding is often used to enable novel study designs, cutting-edge analytic approaches, or exploratory lines of investigation that could reshape how the field understands addiction vulnerability and outcomes, even if the project is earlier than what would typically be considered "R01-ready."
Administratively, the opportunity is categorized as a discretionary grant with the funding activity category listed under education and health, and it is associated with CFDA number 93.279. The funding opportunity number is PAR-16-357, and the program was created on 2016-07-07. The original closing date listed is 2018-01-24, which is important because it suggests this particular posting reflects a past deadline; anyone interested today would normally need to look for a reissued or current version of the announcement rather than assuming the opportunity is still accepting applications under the same dates.
Eligibility is broad across many U.S.-based organization types. Eligible applicants include various levels of government (state, county, city or township, special district), independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, federally recognized Native American tribal governments, and tribal organizations that are not federally recognized. The program also allows nonprofits both with and without 501(c)(3) status (as long as they are not institutions of higher education under those nonprofit categories), public housing authorities/Indian housing authorities, for-profit organizations (other than small businesses), small businesses, and an "other" category that can include additional types depending on NIH definitions. The announcement also explicitly calls out a range of institution types and community-connected organizations as "other eligible applicants," including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.
At the same time, there are clear restrictions related to foreign involvement. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed. In other words, applicants need to be U.S.-based organizations without foreign components in the proposed project structure, which is a stricter stance than some NIH opportunities that may allow certain foreign components when well justified.
In terms of award size, the listed award ceiling is $300,000, but the number of expected awards is not specified in the provided data. Taken together, the structure and intent point to a program that prioritizes investigator promise and innovation over extensive preliminary results, with the practical aim of helping early career researchers establish a transformative research direction in the genetics or epigenetics of substance use disorders.Apply for PAR 16 357
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Avenir Award Program for Genetics or Epigenetics of Substance Use Disorders (DP1)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279.
- This funding opportunity was created on 2016-07-07.
- Applicants must submit their applications by 2018-01-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $300,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 16 357) also looked into and applied for these:
| Funding Opportunity |
|---|
| Social Epigenomics Research Focused on Minority Health and Health Disparities (R21) Apply for PAR 16 356 Funding Number: PAR 16 356 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Social Epigenomics Research Focused on Minority Health and Health Disparities (R01) Apply for PAR 16 355 Funding Number: PAR 16 355 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| International Tobacco, and Health Research and Capacity Building Program (R01) Apply for RFA TW 16 003 Funding Number: RFA TW 16 003 Agency: National Institutes of Health Category: Education, Health Funding Amount: $250,000 |
| Research Infrastructure Development for Interdisciplinary Aging Studies (R21/R33) Apply for PAR 16 367 Funding Number: PAR 16 367 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Advanced-Stage Development and Utilization of Research Infrastructure for Interdisciplinary Aging Studies (R33) Apply for PAR 16 368 Funding Number: PAR 16 368 Agency: National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| Mechanisms of Immune Activation and Inflammation: HIV Infection, ART, and Drugs of Abuse (R01) Apply for RFA DA 17 013 Funding Number: RFA DA 17 013 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Fundamental Mechanisms of Affective and Decisional Processes in Cancer Control (R01) Apply for PAR 16 380 Funding Number: PAR 16 380 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Chemistry Science Track Award for Rapid Transition (C/START) (R03) Apply for PAR 16 383 Funding Number: PAR 16 383 Agency: National Institutes of Health Category: Education, Health Funding Amount: $50,000 |
| Chemical Discovery (CHEM) Award (R21/R33) Apply for PAR 16 384 Funding Number: PAR 16 384 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Oncology Co-Clinical Imaging Research Resources to Encourage Consensus on Quantitative Imaging Methods and Precision Medicine (U24) Apply for PAR 16 385 Funding Number: PAR 16 385 Agency: National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| Surgical Disparities Research (R01) Apply for PAR 16 391 Funding Number: PAR 16 391 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Exploratory/Developmental Surgical Disparities Research (R21) Apply for PAR 16 392 Funding Number: PAR 16 392 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| NIDA Program Project Grant Applications (P01) Apply for PAR 16 393 Funding Number: PAR 16 393 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Secondary Analyses of Alcohol and Chronic Disease (R03) Apply for PA 16 394 Funding Number: PA 16 394 Agency: National Institutes of Health Category: Education, Health Funding Amount: $50,000 |
| Secondary Analyses of Alcohol and Chronic Disease (R01) Apply for PA 16 395 Funding Number: PA 16 395 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Engineering Next-Generation Human Nervous System Microphysiological Systems (R21) Apply for PAR 16 397 Funding Number: PAR 16 397 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| NCI Mentored Clinical Scientist Research Career Development Award to Promote Diversity (K08) Apply for PAR 16 400 Funding Number: PAR 16 400 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Engineering Next-Generation Human Nervous System Microphysiological Systems (R01) Apply for PAR 16 398 Funding Number: PAR 16 398 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Mentored Patient-Oriented Research Career Development Award to Promote Diversity (K23) Apply for PAR 16 399 Funding Number: PAR 16 399 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Mentored Research Scientist Development Award to Promote Diversity (K01) Apply for PAR 16 401 Funding Number: PAR 16 401 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
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